Product Application
Plant essential oil inclusion compound solve their natural defects by inhibiting volatility, enhancing stability, improving bioavailability and controlling release, and expand their applications in the fields of medicine, food, daily chemicals, etc.
1. Inhibit volatility and improve stability
Volatile oils are easy to volatilize and oxidize, resulting in rapid loss of active ingredients during storage or processing.
1) Reduce volatility: The hydrophobic cavity of cyclodextrin wraps the volatile oil molecules, forming a physical barrier, significantly reducing its volatility.
2) Antioxidant protection: The inclusion complex isolates oxygen and light, delaying oxidation reactions.
2. Enhance water solubility and bioavailability
Volatile oils are mostly fat-soluble and poorly water-soluble, limiting their use in oral preparations or water-based products.
1) Improve solubility: After inclusion, the hydrophilic cyclodextrin shell is exposed, allowing the volatile oil components to dissolve in the aqueous phase.
2) Promote absorption: The inclusion complex dissolves rapidly in the intestine, and the absorption efficiency through intestinal epithelial cells is increased by 2-3 times, and the peak blood drug concentration (Cₘₐₓ) and bioavailability are significantly increased.
3. Controlled release and extended action time
By adjusting the structure of the inclusion complex and the type of cyclodextrin, the active ingredients can be sustained or targeted.
1) Sustained release effect: Lavender oil inclusion complex is slowly released in textile fibers, and the fragrance retention time is extended to more than 3 times that of unincluded oil.
2) Environmental response release: Some inclusion complexes dissociate at a specific pH or temperature, such as turmeric oil inclusion complexes, which have an increased release rate in the alkaline environment of the intestine, achieving colon-targeted delivery.
4. Protect active ingredients and enhance synergy
Inclusion technology can protect heat-sensitive or photosensitive components in volatile oils while enhancing their functionality.
1) Improved thermal stability: In baked food processing (180°C), the retention rate of cinnamaldehyde in cinnamon oil inclusion complexes exceeds 90%, while the loss rate of unincluded oil reaches 60%.
2) Synergistic enhancement: Volatile oil and cyclodextrin may produce synergistic effects after inclusion.
5. Reduce irritation and side effects
Direct contact with volatile oils may cause skin or mucous membrane irritation, and inclusion reduces its irritation.
1) Reduce skin irritation: When tea tree oil inclusions are used in skin care products, the incidence of irritation reactions on sensitive skin is reduced by more than 50%.
2) Mask bad odors: Volatile oils with strong odors such as garlic oil can significantly reduce odor after inclusion, improving user acceptance.
6. Expand multi-field applications
Inclusion technology promotes the innovative application of plant volatile oils in medicine, food, agriculture and other fields:
1) Medical field
Antibacterial preparations: Thyme oil inclusions are used in oral sprays to prolong the antibacterial effect time.
Anti-inflammatory transdermal patches: Menthol inclusions relieve muscle pain through sustained release.
2) Food industry field
Natural preservatives: Rosemary oil inclusions are used to preserve meat products and inhibit lipid oxidation.
Flavor stabilizers: Citrus oil inclusions are added to beverages to prevent aroma loss.
3) Daily chemicals and textiles
Slow-fragrance microcapsules: Rose essential oil inclusion compounds are used in fabrics, and the number of washing resistance is increased to more than 10 times.
Functional cosmetics: Tea tree oil inclusion compounds are used in oil control and acne removal products to reduce the risk of allergies.
4) Agriculture and environmental protection
Green pesticides: Lemongrass oil inclusion compounds are used as slow-release insect repellents to reduce the use of chemical pesticides.
Air purification: Eucalyptus oil inclusion compounds are loaded on filter elements to release antibacterial ingredients for a long time.
