Soluble cyclodextrin inclusion compound of Pueraria Flavones

Soluble cyclodextrin inclusion complex of pueraria flavonoids solves the bottleneck problem of pueraria flavonoids application by improving solubility, stability and bioavailability, while expanding its application in the fields of medicine, food, cosmetics, etc.

Product Application

Soluble cyclodextrin inclusion complex of pueraria flavonoids solves the bottleneck problem of pueraria flavonoids application by improving solubility, stability and bioavailability, while expanding its application in the fields of medicine, food, cosmetics, etc.

1. Significantly improve the solubility of pueraria flavonoids
Pueraria flavonoids (such as puerarin) have poor water solubility due to their hydrophobic molecular structure, which limits their application in oral preparations or water-based products. Through the inclusion of cyclodextrin, puerarin is encapsulated in the hydrophobic cavity of cyclodextrin, and the hydrophilic shell is exposed to the water environment, thereby significantly improving its solubility.

2. Enhance chemical stability
Pueraria flavonoids are easily degraded under light, heat or oxidation conditions, affecting the efficacy. Cyclodextrin inclusion forms a physical barrier to reduce the damage of the external environment to the active ingredients.

3. Improve bioavailability
The improvement of solubility and stability directly promotes the absorption efficiency of pueraria flavonoids in the body.

4. Controlled release and sustained release effect
Cyclodextrin inclusion technology can adjust the release rate of active ingredients and achieve long-term effects.

5. Reduce side effects and irritation
Inclusion reduces the irritation of pueraria flavonoids to the digestive tract by reducing the direct contact between pueraria flavonoids and the gastrointestinal mucosa.

6. Expanding application scenarios
The development of soluble inclusion compounds has promoted the application of pueraria lobata flavonoids in multiple fields:
1)Medical field: used for targeted treatment of cardiovascular diseases (such as arteriosclerosis), diabetes, and neurodegenerative diseases (such as Alzheimer’s disease).
2)Food and health products: added to beverages, soft candies, meal replacement powders, etc. as functional ingredients to meet health needs such as anti-oxidation and blood sugar regulation.
3)Cosmetics: using its anti-inflammatory and antioxidant properties to develop skin care products and enhance the transdermal absorption of active ingredients.

7. Promoting the optimization of separation and purification processes
Cyclodextrin bonding technology is not only used for inclusion, but also plays a key role in the separation and purification of pueraria lobata flavonoids.